There are many good tools to mine precious germs in the nano worlds. Of course, they are not always good, and they have advantages and disadvantages based on what we want to know. Here we list the representative computational methods, which are currently utilized in the CAN Lab to investigate the nanomechanics. According to resolutions, they can be categorized into quantum - atomic - (meso) - continuum methods. In addition, ADMD is a specially developed method in order to explore the rare event systems, and Scale-Bridging is a hot topic to merge more than two different resolutions into a single computational framework.